Commercial / Proprietary

  • Claude Agent SDK (Anthropic)
    • The harness behind Claude Code, as a library: file tools, shell execution, permissions, subagents, hooks, and in-process MCP servers
    • MIT-licensed, but built for Claude models only, so it isn’t listed as provider-agnostic
  • Mastra
    • Hosted commercial layer, Mastra Platform (deployment, observability, hosted Studio), under the same brand as the open-source core (see Open Source)

Open Source / Provider-agnostic

Legacy / Decommissioned

  • AutoGen (Microsoft)
    • Superseded by Microsoft Agent Framework 1.0 (April 3, 2026), built by the same team. Now in maintenance mode and community-managed; AG2 continues the codebase
  • Semantic Kernel (Microsoft)
    • Superseded by Microsoft Agent Framework in the same release. Receives critical bug and security fixes only